More than 80 companies currently claim to offer manufacturing related services, at different scales of operations, for a variety of oligonucleotide-based products, claims Roots Analysis


Several big pharma companies are known to outsource more than half of their clinical-stage oligonucleotide manufacturing operations. Anticipating a sharp rise in demand, oligonucleotide manufacturers are increasingly consolidating their portfolios, building new capabilities and expanding their respective capacities, mostly through acquisitions, in order to gain a competitive edge.


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The USD 5.8 billion (by 2030) financial opportunity within the oligonucleotide synthesis, modification and purification services market has been analyzed across the following segments:

  • Type of manufacturing
  • Custom manufacturing
  • Large-scale manufacturing


  • Type of Oligonucleotides manufactured
  • Antisense Oligonucleotides
  • miRNAs
  • shRNAs
  • siRNAs
  • Other Oligonucleotides


  • Scale of operation
  • Clinical
  • Commercial


  • Purpose of production
  • In-house
  • Outsourced


  • Target therapeutic area
  • Autoimmune Disorders
  • Cardiovascular Disorders
  • Genetic Disorders
  • Infectious Diseases
  • Metabolic Disorders
  • Neuromuscular Disorders
  • Oncological Disorders
  • Ophthalmic Disorders
  • Other Therapeutic Areas


  • Size of manufacturer
  • Small
  • Mid-sized
  • Large


  • Key Geographical Region
  • North America
  • Europe
  • Asia-Pacific and Rest of the World


The Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2020-2030”report features the following companies, which we identified to be key players in this domain:

  • Agilent Technologies
  • Ajinomoto Bio-Pharma Services
  • BioSpring
  • CordenPharma
  • Integrated DNA Technologies
  • Kaneka Eurogentec
  • LGC Biosearch Technologies
  • Microsynth
  • Nitto Denko Avecia
  • Sigma Aldrich
  • Thermo Fisher Scientific
  • Trilink Biotechnologies


Table of Contents


  1. 1. Preface

    Executive Summary

  2. Introduction
  3. Market Landscape: Oligonucleotide Manufacturers (Research and Diagnostic Applications)
  4. Market Landscape: Oligonucleotide Manufacturers (Therapeutic Applications)
  5. Company Competitiveness Analysis: Oligonucleotide Manufacturers (Research and Diagnostic Applications)
  6. Company Competitiveness Analysis: Oligonucleotide Manufacturers (Therapeutic Applications)
  7. Company Profiles: Oligonucleotide Manufacturers (Research and Diagnostic Applications)
  8. Company Profiles: Oligonucleotide Manufacturers (Therapeutic Applications)
  9. Partnerships and Collaborations
  10. Recent Expansions
  11. Clinical Trial Analysis


  1. Capacity Analysis


  1. Demand Analysis
  2. Market Sizing and Opportunity Analysis


  1. Swot Analysis
  2. Survey Analysis


  1. Executive Insights


  1. Concluding Remarks


  1. Appendix 1: Tabulated Data


  1. Appendix 2: List of Companies and Organizations


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Contact Details

Gaurav Chaudhary

+1 (415) 800 3415


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