Corticosteroid-Responsive Dermatoses Market : Emerging Industry Volume & Analysis 2014 – 2020
Dermatosis is a condition wherein the outer layer of the body, namely the skin (dermis) or hair, nail, etc has an irritation or an anomaly. Dermatoses involve condition of the skin that does not involve inflammation. In cases of inflammation, they are termed dermatitis. Corticosteroids are usually used to treat inflammation, but it is observed that corticosteroids sometimes also helped alleviate dermatoses. Dermatoses can be categorized as a cutaneous condition with following types of disorders: rheumatoid neutrophilic dermatoses, acute febrile neutrophilic dermatoses, dermatoses papulosa nigra, dermatoses neglecta, dermatoses cinecienta, linear lichenoid dermatoses, digitate dermatoses, contagious pustular dermatoses, transient acantholytic dermatoses, juvenile plantar dermatoses, etc to name a few. Corticosteroids, besides their inflammation control action are useful in treating disorders that are caused by hyperactivity of the immune response. They were first discovered in the adrenal cortex region of mammals; nowadays, they are synthetically designed variants of steroid hormones and are used to regulate immune response, stress and inflammation along with control of carbohydrate metabolism, blood electrolyte levels, and protein catabolism. Corticoids are of generally two types:
Glucose based, hence named glucocorticoids, which regulate glucose/ carbohydrates/fats/proteins and thereby assist in controlling inflammation. E.g Cortisol
Mineral based, hence named mineralocorticoids, which regulate/control water level in the body buy controlling sodium retention. E.g aldosterone, corticosterone, etc
Corticosteroids’ use is accompanied by side effects, particularly allergic responses in some severe cases reported. This is why generally corticosteroids aren’t used to treat dermatoses, but some conditions like non-infectious dermatoses, etc, it has been found to be extremely useful. Clobetasol Propionate is one such example which has been prescribed to control inflammatory responses in common dermatoses as a topical medical aid. It showed 99% success rate in treating cases of psoriasis and other corticosteroid-responsive dermatoses.
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